Impact of a school-based intervention on sugar-sweetened beverage intake substitution by water in Mexican scholars.

INTRODUCTION: The prevalence of overweight and obesity in children has increased in recent years, associated with substituting plain water intake with sugar-sweetened beverages. To evaluate the impact of a school-based intervention that aimed to replace sugar-sweetened beverages with water in Mexican scholars. METHODS: We included 314 children aged 9-11 from three public schools of the State of Hidalgo, Mexico, randomized to intervention (two schools from the municipality of Apan; six classes with 146 participants) or control group (one school from the municipality of Emiliano Zapata; six classes with 168 participants) and followed for six months. The intervention consisted of placing drinking fountains at school and classrooms with nutritional education lessons to increase water consumption and decrease sugar-sweetened beverages. Mixed models for repeated measures were used to assess the impact of the intervention. RESULTS: At the end of the study, water consumption was higher (200 mL/day, p=0.005), and flavored milk consumption was lower (94 mL/day, p=0.044) in the intervention group compared with the control group. There was also a statistically significant reduction for energy (p=0.016) and sugar intake (p=0.007). CONCLUSIONS: The school-based intervention favorably modified the consumption pattern of sugar-sweetened beverages and water in Mexican students.

Adherence to school meals and co-occurrence of the healthy and unhealthy food markers among Brazilian adolescents.

The aim of this study was to analyze the association between adherence to school meals and the co-occurrence of the regular consumption of healthy and unhealthy eating markers among Brazilian adolescents. Data from 67,881 adolescents in Brazilian public schools who participated in the 2015 National School Health Survey, were used. From the 7-day FFQ, the dependent variable was constructed, co-occurrence of regular consumption (≥ 5x/week) of healthy and unhealthy food markers, which was categorized as regular consumption of none, one or two, or three eating markers. We performed an ordinal logistic regression with adjustment for sociodemographic, eating habits outside of school, and school characteristics variables. The prevalence of the co-occurrence of the regular consumption of three healthy eating markers was 14.5%, and that of three unhealthy markers was 4.9%. High adherence to school meals (every day) was positively associated with regular consumption of healthy eating markers and inversely associated with regular consumption of unhealthy eating markers. The school meals provided by PNAE contribute to the promotion of healthy eating habits among Brazilian adolescents.

Adherence to school meals and co-occurrence of the healthy and unhealthy food markers among Brazilian adolescents / Adesão à alimentação escolar e coocorrência dos marcadores de alimentação saudável e não saudável entre adolescentes brasileiros

Abstract The aim of this study was to analyze the association between adherence to school meals and the co-occurrence of the regular consumption of healthy and unhealthy eating markers among Brazilian adolescents. Data from 67,881 adolescents in Brazilian public schools who participated in the 2015 National School Health Survey, were used. From the 7-day FFQ, the dependent variable was constructed, co-occurrence of regular consumption (≥ 5x/week) of healthy and unhealthy food markers, which was categorized as regular consumption of none, one or two, or three eating markers. We performed an ordinal logistic regression with adjustment for sociodemographic, eating habits outside of school, and school characteristics variables. The prevalence of the co-occurrence of the regular consumption of three healthy eating markers was 14.5%, and that of three unhealthy markers was 4.9%. High adherence to school meals (every day) was positively associated with regular consumption of healthy eating markers and inversely associated with regular consumption of unhealthy eating markers. The school meals provided by PNAE contribute to the promotion of healthy eating habits among Brazilian adolescents.

Resumo Este estudo tem como objetivo analisar a associação entre a adesão à alimentação escolar e a coocorrência do consumo regular de marcadores de alimentação saudável e não saudável entre adolescentes brasileiros. Foram avaliados 67.881 adolescentes de escolas públicas brasileiras participantes da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015. A partir do QFA de sete dias, construiu-se a variável dependente, coocorrência do consumo regular (≥ 5x/semana) de marcadores de alimentação saudável e não saudável, que foi categorizada em consumo regular de nenhum; um ou dois; ou três marcadores de alimentação. Realizou-se regressão logística ordinal com ajuste para variáveis sociodemográficas, hábitos alimentares fora da escola e características da escola. A prevalência da coocorrência do consumo regular de três marcadores de alimentação saudável foi de 14,5%, e de três marcadores de alimentação não saudável foi de 4,9%. A alta adesão à alimentação escolar (todos os dias) foi positivamente associada ao consumo regular de marcadores de alimentação saudável e inversamente associada ao consumo regular de marcadores de alimentação não saudável. A alimentação escolar fornecida pelo PNAE contribui para a promoção de hábitos alimentares saudáveis entre os adolescentes brasileiros.

Colorectal cancer survival in Greater Cuiabá, state of Mato Grosso, Brazil. / Sobrevida do câncer colorretal na Grande Cuiabá, Mato Grosso, Brasil.

OBJECTIVE: To analyze the specific five-year survival of colorectal cancer (CRC) diagnosed between 2008 and 2013, according to sex and age group, of residents in Greater Cuiabá, state of Mato Grosso, Brazil. METHODS: This is a retrospective cohort study. Specific survival of CRC was considered as the time between disease diagnosis and death from CRC, in months. Data from the Population-Based Cancer Registry and the Brazilian Mortality Information System were used. To estimate the probability of survival by sex and age group, the Kaplan-Meier estimator was used, and to estimate the effect of age group on the survival of participants, the Cox model stratified by sex was adjusted. RESULTS: From 2008 to 2013, 683 new cases and 193 deaths from CRC were registered. The median time between diagnosis and death from CRC was 44.8 months (95%CI 42.4- 47.3) for women and 46.1 months (95%CI 43.4-48.6) for men, and the five-year survival probabilities of 83.5% (95%CI 79.9-87.2%) and 89.6% (95%CI 86.4-93.0%), respectively. Men aged 70-79 years (HR=2.97; 95%CI 1.11-3.87) and 80 years or older (HR=3.09; 95%CI 1.31-7.27) were at higher risk of mortality, and we verified no difference for women. CONCLUSION: Women had a shorter time between the diagnosis of CRC and death from the disease as well as a lower probability of survival. Conversely, men were at higher risk of mortality after 70 years of age.

OBJETIVO: Analisar a sobrevida específica em cinco anos do câncer colorretal diagnosticado entre 2008 e 2013, segundo sexo e faixa etária, de residentes na Grande Cuiabá, Mato Grosso. MÉTODOS: Estudo de coorte retrospectiva. A sobrevida específica pelo câncer colorretal foi considerada como o tempo entre o diagnóstico da doença até o óbito por câncer colorretal, em meses. Utilizaram-se dados do Registro de Câncer de Base Populacional e do Sistema de Informações sobre Mortalidade. Para estimar a probabilidade de sobrevida por sexo e faixa etária, utilizou-se o estimador de Kaplan-Meier, e, para estimar o efeito da faixa etária na sobrevida dos participantes, foi ajustado modelo de Cox estratificado por sexo. RESULTADOS: De 2008 a 2013, registraram-se 683 casos novos e 193 óbitos por câncer colorretal. O tempo mediano entre o diagnóstico e a morte por câncer colorretal foi de 44,8 meses (IC95% 42,4­47,3) para as mulheres e 46,1 meses (IC95% 43,4­48,6) para os homens e a probabilidade de sobrevida em cinco anos de 83,5% (IC95% 79,9­87,2%) e 89,6% (IC95% 86,4­93,0%), respectivamente. Os homens com 70-79 anos (HR=2,97; IC95% 1,11­3,87) e com 80 anos ou mais (HR=3,09; IC95% 1,31­7,27) apresentaram maior risco de mortalidade e sem diferença para as mulheres. CONCLUSÃO: O sexo feminino apresentou menor tempo entre o diagnóstico e o óbito pela doença, assim como menor probabilidade de sobrevida. Em contrapartida, foram os homens que apresentaram maior risco de mortalidade a partir dos 70 anos.

Sobrevida do câncer colorretal na Grande Cuiabá, Mato Grosso, Brasil / Colorectal cancer survival in Greater Cuiabá, state of Mato Grosso, Brazil

RESUMO Objetivo: Analisar a sobrevida específica em cinco anos do câncer colorretal diagnosticado entre 2008 e 2013, segundo sexo e faixa etária, de residentes na Grande Cuiabá, Mato Grosso. Métodos: Estudo de coorte retrospectiva. A sobrevida específica pelo câncer colorretal foi considerada como o tempo entre o diagnóstico da doença até o óbito por câncer colorretal, em meses. Utilizaram-se dados do Registro de Câncer de Base Populacional e do Sistema de Informações sobre Mortalidade. Para estimar a probabilidade de sobrevida por sexo e faixa etária, utilizou-se o estimador de Kaplan-Meier, e, para estimar o efeito da faixa etária na sobrevida dos participantes, foi ajustado modelo de Cox estratificado por sexo. Resultados: De 2008 a 2013, registraram-se 683 casos novos e 193 óbitos por câncer colorretal. O tempo mediano entre o diagnóstico e a morte por câncer colorretal foi de 44,8 meses (IC95% 42,4-47,3) para as mulheres e 46,1 meses (IC95% 43,4-48,6) para os homens e a probabilidade de sobrevida em cinco anos de 83,5% (IC95% 79,9-87,2%) e 89,6% (IC95% 86,4-93,0%), respectivamente. Os homens com 70-79 anos (HR=2,97; IC95% 1,11-3,87) e com 80 anos ou mais (HR=3,09; IC95% 1,31-7,27) apresentaram maior risco de mortalidade e sem diferença para as mulheres. Conclusão: O sexo feminino apresentou menor tempo entre o diagnóstico e o óbito pela doença, assim como menor probabilidade de sobrevida. Em contrapartida, foram os homens que apresentaram maior risco de mortalidade a partir dos 70 anos.

ABSTRACT Objective: To analyze the specific five-year survival of colorectal cancer (CRC) diagnosed between 2008 and 2013, according to sex and age group, of residents in Greater Cuiabá, state of Mato Grosso, Brazil. Methods: This is a retrospective cohort study. Specific survival of CRC was considered as the time between disease diagnosis and death from CRC, in months. Data from the Population-Based Cancer Registry and the Brazilian Mortality Information System were used. To estimate the probability of survival by sex and age group, the Kaplan-Meier estimator was used, and to estimate the effect of age group on the survival of participants, the Cox model stratified by sex was adjusted. Results: From 2008 to 2013, 683 new cases and 193 deaths from CRC were registered. The median time between diagnosis and death from CRC was 44.8 months (95%CI 42.4- 47.3) for women and 46.1 months (95%CI 43.4-48.6) for men, and the five-year survival probabilities of 83.5% (95%CI 79.9-87.2%) and 89.6% (95%CI 86.4-93.0%), respectively. Men aged 70-79 years (HR=2.97; 95%CI 1.11-3.87) and 80 years or older (HR=3.09; 95%CI 1.31-7.27) were at higher risk of mortality, and we verified no difference for women. Conclusion: Women had a shorter time between the diagnosis of CRC and death from the disease as well as a lower probability of survival. Conversely, men were at higher risk of mortality after 70 years of age.

Skipping breakfast associated with socioeconomic and lifestyle factors in Brazilian adolescents / Omitir o café da manhã está associado a fatores socioeconômicos e de estilo de vida entre adolescentes brasileiros

Abstract The aim is to estimate the prevalence and evaluate the association of socioeconomic and lifestyle factors with skipping breakfast among Brazilian adolescent students. A cross-sectional study carried out with adolescent ninth-graders from Brazilian public and private schools participating in the 2015 National School Health Survey. The prevalence of skipping breakfast (less than five days/week) and its respective 95% confidence intervals were estimated and stratified by gender according to demographic, socioeconomic, and lifestyle factors, self-perceived body image, and attitudes towards weight. A three-block hierarchical Poisson regression, considering the complex sample design. The prevalence of skipping breakfast was 35.6%, higher among girls than boys. In both genders, skipping breakfast was positively associated with the highest socioeconomic level, morning school shift, paid work, regular consumption of alcoholic beverages, living only with the mother, the father or neither, the irregular consumption of school food and meals with parents, considering oneself too fat/fat and trying to lose weight. In general, skipping breakfast was associated with socioeconomic factors and lifestyle behaviors harmful to health among adolescent students.

Resumo O objetivo é estimar a prevalência e avaliar a associação dos fatores socioeconômicos e de estilo de vida com a omissão do café da manhã entre adolescentes escolares brasileiros. Um estudo transversal realizado com adolescentes do 9º ano de escolas públicas e privadas brasileiras participantes da Pesquisa Nacional de Saúde do Escolar de 2015. A prevalência de omissão do café da manhã (menos de cinco dias/semana) e seus respectivos intervalos de confiança de 95% foram estimados e estratificados por sexo de acordo com fatores demográficos, socioeconômicos, estilo de vida, autopercepção da imagem corporal e atitudes em relação ao peso. Uma regressão de Poisson hierárquica de três blocos, considerando o desenho amostral complexo. A prevalência de pular o café da manhã foi de 35,6%, maior entre as meninas do que entre os meninos. Em ambos os sexos, omitir o café da manhã associou-se positivamente com maior nível socioeconômico, turno escolar matutino, trabalho remunerado, consumo regular de bebidas alcoólicas, morar apenas com a mãe, pai ou nenhum dos dois, consumo irregular de alimentação escolar e refeições com os pais, considerar-se muito gordo/gordo e tentar perder peso. Em geral, a omissão do café da manhã foi associada a fatores socioeconômicos e comportamentos de estilo de vida prejudiciais à saúde entre estudantes adolescentes.

Skipping breakfast associated with socioeconomic and lifestyle factors in Brazilian adolescents.

The aim is to estimate the prevalence and evaluate the association of socioeconomic and lifestyle factors with skipping breakfast among Brazilian adolescent students. A cross-sectional study carried out with adolescent ninth-graders from Brazilian public and private schools participating in the 2015 National School Health Survey. The prevalence of skipping breakfast (less than five days/week) and its respective 95% confidence intervals were estimated and stratified by gender according to demographic, socioeconomic, and lifestyle factors, self-perceived body image, and attitudes towards weight. A three-block hierarchical Poisson regression, considering the complex sample design. The prevalence of skipping breakfast was 35.6%, higher among girls than boys. In both genders, skipping breakfast was positively associated with the highest socioeconomic level, morning school shift, paid work, regular consumption of alcoholic beverages, living only with the mother, the father or neither, the irregular consumption of school food and meals with parents, considering oneself too fat/fat and trying to lose weight. In general, skipping breakfast was associated with socioeconomic factors and lifestyle behaviors harmful to health among adolescent students.

Cancer surveillance in Mato Grosso, Brazil: methodological and operational aspects of a university extension/research project.

OBJECTIVE: To describe the methodological and operational aspects of the "Project for surveillance of cancer and its associated factors: population-based and hospital-based registry" (VIGICAN), in the state of Mato Grosso (MT), Brazil. METHODS: VIGICAN was divided into two projects: a university extension one, which updated the data from the Population-based Cancer Registry (PBCR) of MT in the 2008-2016 period; and a research project, which collected primary data, through individual interviews and analysis of medical records of people with a diagnosis of cancer, aged 18 years or older, treated at reference hospitals for oncology. To analyze the factors associated with cancer, the following variables were collected: socioeconomic and demographic, social support, health status and behavior, and environmental exposure. RESULTS: In the 2008-2016 period, approximately one hundred thousand cases of cancer (incident and prevalent) were reported in the PBCR Cuiabá and PBCR Interior. After validation procedures, 50 thousand incident cases were elected. The survey interviewed 1,012 patients, 38.2% living in the municipalities of Cuiabá and Várzea Grande, 60.4% in small cities of the state, and 1.4% in other states. Preliminary data showed that the majority were women (55.0%) and younger than 60 years of age (54.3%). Among the interviewees, 7.2% reported smoking tobacco, 15.5% consumed alcoholic beverages (15.5%), and 32.7% lived nearby crops. CONCLUSION: The development of these projects allowed the integration of education with health services and will enable the recognition of specificities and different exposure scenarios and factors associated with cancer in the Mato Grosso territory.

Trend of incompleteness of cancer death records in the Mortality Information System database, state of Mato Grosso, Brazil, 2000 to 2016.

OBJECTIVE: To describe the trend of incompleteness of cancer death records in the Mortality Information System (SIM, in Portuguese) database, state of Mato Grosso, Brazil, 2000 to 2016. METHODS: This is a descriptive, ecological, time series study of records of death from cancer of people living in the state of Mato Grosso (codes C00 to C97 of the 10th revision of the International Statistical Classification of Diseases and Related Health Problems - ICD-10), collected from SIM. To asses incompleteness in the filling of the variables of race/skin color, education, marital status, occupation and underlying cause of death, the relative frequency was calculated in the percentage of null values. The time trend analyzes of the incomplete percentage of categories and variables of interest was performed using linear regression (p<0.05). RESULTS: From 2000 to 2016, there were 31,097 deaths from cancer among residents of the state of Mato Grosso. Race/skin color, marital status and occupation presented a stable trend of incompleteness; education and underlying cause of death were decreasing. An increasing trend was observed in the categories ignored (marital status) and retired (occupation); a decreasing trend was observed for blank (education), unidentified and housewife (occupation), and C76-other and ill-defined sites and C80-without specification of site (underlying cause of death). Incompleteness of occupation was classified as very poor, with emphasis on housewife and retired. For the remaining variables and categories, the classification was excellent or good. CONCLUSIONS: Although most of the indicators showed satisfactory trend and classification, the marital status and occupation variables stood out for indicating poorer quality in the records.

Mortality trend of cancer and main types according to macroregion in the state of Mato Grosso, Brazil, 2000 to 2015.

OBJECTIVE: To describe the mortality trend from all cancers and the five main ones in the state of Mato Grosso, Brazil, from 2000 to 2015. METHODS: This is a descriptive, ecological, time series study, with data referring to deaths of residents of Mato Grosso due to cancer (ICD-10 codes C00 to C97), from the Mortality Information System (SIM). Time trend analyses of the standardized mortality rate from all cancers and five specific cancers (lung, prostate, breast, colorectal and cervical) for the state and according to macroregion (South, West, North, East and Center-North) were performed using linear regression (p<0.05). RESULTS: From 2000 to 2015, 28,525 deaths from all cancers in residents of the state of Mato Grosso were recorded. An increasing trend was observed for all cancers, in addition to lung, breast and colorectal cancers. The South and North macroregions showed an increasing trend for all cancers, breast and colorectal, and Center-North for breast and colorectal. East showed an increasing trend for all cancers, prostate and colorectal, and decreasing for cervical. CONCLUSION: In the state of Mato Grosso, there was an increasing trend in mortality for all cancers and from specific ones, with emphasis on breast and colorectal cancer in most macroregions.

Colorectal cancer mortality trend in Mato Grosso, Brazil, 2000 to 2019.

OBJECTIVE: To analyze the time series of colorectal cancer (CRC) mortality, according to sex and age group, in Mato Grosso, Brazil, from 2000 to 2019. METHODS: Ecological time series study, with standardized mortality rates from CRC (C18 to C21) among residents of Mato Grosso. Information on deaths was provided by the Mato Grosso State Health Department, comprising the Mortality Information System and demographic information obtained from the Brazilian Institute of Geography and Statistics. The joinpoint regression analysis was used in the analysis of temporal trend. RESULTS: A total of 2,406 deaths from CRC were identified in Mato Grosso between 2000 and 2019. The highest rates were found among the age group from 60 to 79 years. There was an increasing trend in mortality rates among men due to CRC for almost all age groups, with the exception of those aged 40 to 49 years and 80 years and older. For women, there was a significant increase in the age groups from 50 to 59 years and 80 years and older. CONCLUSION: The results showed an increase in mortality rates from CRC in the state of Mato Grosso, from 2000 to 2019, in certain age groups for both sexes, but especially for men. Knowledge about the evolution of mortality can provide data on the epidemiological situation of cancer at the local level and, thus, contribute to the development of actions to control and prevent this disease.

Incidence and Mortality by the Main Types of Cancer in the City of Cuiabá, Mato Grosso, Between the Years of 2008 and 2016.

OBJECTIVE: To analyze the temporal trend of the incidence and mortality rate for prostate, breast, colorectal, lung, cervical, stomach and laryngeal cancer among residents in the city of Cuiabá between 2008 and 2016. METHODS: Time series study with data from the Mortality Information System and the Population-Based Cancer Registry. Stratified by sex, the proportional distribution of new cases and deaths by age group and the cancer incidence and mortality rates standardized by the world population were calculated. Linear regression was used and the annual percentage change (APC) was estimated. RESULTS: In males, most new cases and deaths, for the main types of cancer, occurred among those aged 50 years or older, and the incidence rate of prostate cancer showed a tendency to decrease in the period (APC=-4.33%). For females, the proportion of new cases and deaths, due to breast and cervical cancer, were more frequent among women aged 50 years or younger, and lung, stomach and colorectal cancer among women aged 50 years or older. The incidence rate of breast cancer showed an increasing trend (APC=3.60%). For both sexes, the mortality rate remained stable. CONCLUSION: The incidence rate trend varied between sexes, an increase was observed for breast cancer among women and a reduction for prostate cancer among men. The mortality rate for the main types of cancer was stable.

Incidence trend of five main causes of cancer, in greater Cuiabá, Mato Grosso, Brazil, 2000 to 2016.

OBJECTIVE: To analyze the incidence trend of the five main causes of cancer, according to sex and age, in Greater Cuiabá, in the state of Mato Grosso, from 2000 to 2016. METHODS: Incidence information was obtained from the Population-Based Cancer Registry, referring to the municipalities Cuiabá and Várzea Grande (RCBP - Cuiabá). Crude incidence rates were calculated and the five main types of cancer were selected: for males, prostate (C61), lung (C33-34), colorectal (C18-21), stomach (C16) and oral cavity cancer (C00-10); and for females, breast (C50), cervix (C53), colorectal (C18-21), lung (C33-34) and thyroid gland cancer (C73). Age-adjusted rates were calculated by the direct method, using the world population as reference. Trends were estimated using the Joinpoint method and evaluated by Annual Percent Change (APC) and Average Annual Percent Change (AAPC). The Joinpoint Regression Program software, version 8.3.6.1, was used. RESULTS: During the period, there was a decreasing trend of lung (AAPC=-2.2; 95%CI -4.0--0.3) and stomach cancer (AAPC=-5.2; 95%CI -7.7--2.6) in men, and of cervix cancer (AAPC=-7.2; 95%CI -9.0--5.3) in women, and increasing for breast (AAPC=2.8; 95%CI 0.2-5.5) and thyroid cancer (AAPC=8.3; 95%CI 4.6-12.2). CONCLUSION: In Greater Cuiabá, we found a downward incidence trend among elderly men for prostate, lung and stomach cancer. Women are affected at younger age groups, with an upward trend for breast cancer and downward trend for cervix cancer.

Trends in the incidence of colorectal cancer in Greater Cuiabá, Mato Grosso (Brazil), from 2000 to 2016.

OBJECTIVE: To analyze the temporal incidence trend of colorectal cancer (CRC), according to sex and age, in the Greater Cuiabá, Mato Grosso, Brazil, from 2000 to 2016. METHODS: Ecological time series study, with cases of CRC (C18 to C21) diagnosed from 2000 to 2016, of residents of the Greater Cuiabá (Cuiabá and Várzea Grande), in Mato Grosso. The information on the cases was obtained from the Population-Based Cancer Registry and population data from the Brazilian Institute of Geography and Statistics (IBGE). The rates were adjusted by world population. The age groups considered ranged from 30 to 39 years, 40 to 49 years, 50 to 59 years, 60 to 69 years, 70 to 79 years and 80 years and older. Joinpoint regression was used to analyze the trend of incidence. RESULTS: A total of 1,715 cases of CRC were registered with information on sex and age, with an adjusted rate of 16.4 new cases/100,000 men and 16.1 new cases/100,000 women. Men presented trend of increasing incidence rates in the age group of 70 to 79 years, with increase of 4.0% per year, while women presented trend of increase in the age group 50 to 59 years, with increase of 2.7% per year. CONCLUSION: Older men showed a more significant trend towards an increase in the incidence of CRC, but in women this occurred in a younger age group, highlighting the importance of considering age related information in the analyzes of occurrence of the disease in this population.

Stomach cancer incidence and mortality in Greater Cuiabá, Mato Grosso, Brazil, 2000-2016.

OBJECTIVE: To analyze the incidence and mortality trend of stomach cancer in the Greater Cuiabá, in the state of Mato Grosso, Brazil, from 2000 to 2016. METHODS: The incidence information was obtained from the Population-Based Cancer Registry, and the mortality information from the Mortality Information System. Crude and standardized rates were calculated using the direct method, with the world population as reference. The trends were estimated using the Joinpoint regression method, according to sex and age group, and evaluated through the Annual Percent Change (APC) and the Average Annual Percent Change (AAPC). The Joinpoint Regression Program software, version 4.9.0.0, was used. RESULTS: There was a decreasing incidence trend of stomach cancer in males (AAPC=-5.2; 95% confidence interval - 95%CI -7.7--2.6), in men aged 60 to 69 years (AAPC=-3.7; 95%CI -5.6--1.8) and in 70-79 years (AAPC=-3.7; 95%CI -5.6--1.8), as well as in women aged 50 to 59 years (AAPC=-5.2; 95%CI -7.8--2.6) and 80 years or older (AAPC=-5.2; 95%IC -7.8--2.6). The mortality initially increased in women aged 60-69 years (AAPC=28.4; 95%CI 9.7-50.4), decreased for 80 years or older (AAPC=-26.4; 95%CI -38.0--12.6) and stable for the other age groups and males. CONCLUSION: A decreasing incidence trend of stomach cancer was found among men and, when analyzed by age, among elderly males and adults and elderly females, as well as a stability in the mortality, with an initial variation in elderly women. The production of regional information supports the planning of local policies aimed at reducing the burden of disease and deaths, considering unequal risk conditions and access to health services.

Cervical cancer specific survival in Grande Cuiabá, Mato Grosso State, Brazil.

OBJECTIVE: To estimate specific five-year survival in women diagnosed with cervical cancer living in the municipalities of Cuiabá and Várzea Grande, in the state of Mato Grosso, Brazil. METHODS: This is a retrospective cohort study with information from the Cuiabá Population-based Cancer Registry and the Mortality Information System. To estimate the probability of specific survival in five years, the Kaplan-Meier estimator and the log-rank test were used aiming at verifying if there were statistical differences in the lifetime per groups. To verify the proportionality of the failure rates, the Schoenfeld residual test was used according to the statistical significance level of 0.05. RESULTS: Specific five-year survival and median time were 90.0% and 50.3 months, respectively, for cervical cancer. When analyzing by age, the highest specific survival was among women aged 20 to 49 years (91.7%) and median time was 53.3 months. For the histological type, the highest specific survival was among women with adenocarcinoma (92.3%) and the mean survival time was 53.5 months. CONCLUSION: This study showed that specific survival after five years of diagnosis remained about 90% in patients with cervical cancer. Patients aged 20 to 49 years had higher specific survival and there was statistically significant difference only between age groups.

Incidence, mortality and survival of prostate cancer in two municipalities with a high human development index in Mato Grosso, Brazil.

OBJECTIVE: To analyze the incidence, mortality and survival of prostate cancer in Cuiabá and Várzea Grande, Brazil from 2000 to 2016. METHODS: Data from the Population-based Cancer Registry and the Mortality Information System were used. Mortality and incidence trends were analyzed using joinpoint regression models by age group. Survival analyses were performed using the Kaplan-Meier method, and hazard ratio was estimated by age group. RESULTS: From 2000 to 2016, 3,671 new cases and 892 deaths for prostate cancer were recorded. The average incidence and mortality rates were 87.96 and 20.22 per 100,000, respectively. Decreasing incidence trend was noted for all age groups from 2006 to 2016 (APC=-3.2%) and for men with 80+ years of age from 2000 to 2016 (APC=-3.0%), and increasing mortality trend for men 60-69 years of age from 2000 to 2009 (APC=3.2%). The specific five-year survival rate for prostate cancer was 79.6% (95%CI 77.2-81.9), and the rate decreased with advanced age (HR=2.43, 95%CI 1.5-3.9, for those 70 to 79 years old and HR=7.20, 95%CI 4.5-11.5, for those 80 or older). CONCLUSION: The incidence rate of prostate cancer showed a decreasing trend from 2006 for all age groups; the mortality rate was stable in that period, and worse prognosis was observed in men 70 years or older.

Factors associated with death among cancer patients hospitalized for COVID-19 in Mato Grosso, Brazil.

OBJECTIVE: To analyze the prognostic factors for death from COVID-19 among cancer patients. METHODS: This is a retrospective study based on data recorded in the reporting system for COVID-19 hospitalizations in Mato Grosso. We assessed cases of cancer patients reported between April 2020 and June 2021. We calculated absolute and relative frequencies of sociodemographic variables, hospital care variables, and comorbidities, as well as mean, median, and standard deviation of age and length of stay. Odds ratios and their respective 95% confidence intervals (95%CI) - crude and adjusted - were estimated using the logistic regression model. RESULTS: We analyzed 948 cancer patients hospitalized for COVID-19 in Mato Grosso, with a mean age of 59.7 years. The proportion of deaths was 34.5%, the mortality rate was 3.73 deaths/day (95%CI 3.35-4.16), and the median time between admission and death was 18 days. The likelihood of death was greater among patients aged 60 years or older, with chronic lung disease, who were admitted directly to intensive care units, and required mechanical ventilation at the time of admission. Patients hospitalized from April to December 2020 and January to March 2021 had a greater chance of death than those hospitalized between April and June 2021. CONCLUSION: The likelihood of death from COVID-19 was greater in cancer patients hospitalized before their vaccination period in the state, as well as among older individuals and those admitted in worse clinical conditions.

Cancer surveillance in Mato Grosso: methodological and operational aspects of a extension/research projects / Vigilância do câncer em Mato Grosso: aspectos metodológicos e operacionais de um projeto de extensão/pesquisa

Objective: To describe the methodological and operational aspects of the Cancer Surveillance Project and its associated factors: population-based and hospital-based registry (VIGICAN), in Mato Grosso (MT). Methods: VIGICAN was divided into two projects: an extension one, which updated the data from the Population-Based Cancer Registry (RCBP) of MT in the period 2008 to 2016; and one of research, which collected primary data, through individual interviews and analysis of medical records of people with a diagnosis of cancer, aged 18 years or over, treated at reference hospitals for oncology. To analyze the factors associated with cancer, the following variables were collected: socioeconomic and demographic, social support, status and health behavior, and environmental exposure. Results: In the períod from 2008 to 2016, approximately one hundred thousand cases of cancer (incident and prevalent) were reported in the RCBP Cuiabá and Interior. After validation procedures, fifty thousand incident cases were chosen. The survey interviewed 1,012 patients, 38.2% living in the municipalities of Cuiabá and Várzea Grande, 60.4% in the interior of the state and 1.4% in other states. Preliminary data revealed that the majority were female (55.0%) and younger than 60 years (54.3%). Among those interviewed, 7.2% reported smoking tobacco, 15.5% consumed alcoholic beverages (15.5%) and 32.7% lived close to crops. Conclusion: The development of these projects allowed the integration of education with health services and will enable the recognition of specificities and different exposure scenarios and factors associated with cancer in the Mato Grosso territory.

Objetivo: Descrever os aspectos metodológicos e operacionais do Projeto Vigilância do Câncer e seus fatores associados: registro de base populacional e hospitalar (VIGICAN), em Mato Grosso (MT). Métodos: O VIGICAN se desdobrou em dois projetos: um de extensão, que atualizou os dados dos Registros de Câncer de Base Populacional (RCBP) de MT no período de 2008 a 2016; e um de pesquisa, que coletou dados primários, por meio de entrevistas individuais e análise de prontuários de pessoas com diagnóstico de câncer, com 18 anos ou mais, atendidas em hospitais de referência para oncologia. Para analisar os fatores associados ao câncer, foram coletadas as seguintes variáveis: socioeconômicas e demográficas, suporte social, situação e comportamentos de saúde e exposição ambiental. Resultados: No período de 2008 a 2016, foram notificados nos RCBP Cuiabá e Interior, aproximadamente, 100 mil casos de câncer (incidentes e prevalentes). Após procedimentos de validação, foram eleitos 50 mil casos incidentes. A pesquisa entrevistou 1.012 pacientes, sendo 38,2% residentes nos municípios de Cuiabá e Várzea Grande, 60,4% no interior do estado e 1,4% em outros estados. Os dados preliminares revelaram que a maioria era do sexo feminino (55,0%) e tinha menos de 60 anos (54,3%). Entre os entrevistados, 7,2% relataram fumar tabaco, 15,5% consumiam bebidas alcoólicas (15,5%) e 32,7% moravam próximos a lavouras. Conclusão: O desenvolvimento desses projetos permitiu a integração do ensino com os serviços de saúde e possibilitará o reconhecimento das especificidades e diferentes cenários de exposição e fatores associados ao câncer do território mato-grossense.

Incidence, mortality and survival of prostate cancer in two municipalities with a high human development index in Mato Grosso / Incidência, mortalidade e sobrevida do câncer de próstata em dois municípios com alto Índice de Desenvolvimento Humano de Mato Grosso

Objective: To analyze the incidence, mortality and prostate cancer survival in Cuiabá and Várzea Grande, from 2000 to 2016. Methods: Data from the Population-Based Cancer Registry and the Mortality Information System were used. Mortality and incidence trends analyses were performed using joinpoint regression models by age group. Survival analyses were performed using Kaplan-Meier method and hazard ratio was estimated by age group. Results: From 2000 to 2016, 3,671 new cases and 892 deaths for prostate cancer were recorded. The average incidence and mortality rates were 87.96 and 20.22 per 100,000, respectively. Decreasing incidence trend was noted for all age groups from 2006 to 2016 (APC = -3.2%) and for men with 80+ years of age from 2000 to 2016 (APC = -3.0%), and increasing mortality trend for men 60-69 years of age from 2000 to 2009 (APC = 3.2%). Prostate cancer specific five-year survival rate was 79.6% (CI95%: 77.2; 81.9), and the rate decreased with the advanced age (HR = 2.43, CI95%: 1,5;3,9 for those with 70 to 79 years old and HR = 7.20; CI95%: 4.5;11.5 for those with 80 years old or more). Conclusion: The incidence rate of prostate cancer presented a decreasing trend from 2006, for all age groups, the mortality rate was stable in the period, and worse prognosis was observed in men with 70 years old or more.

Objetivo: analisar a incidência, a mortalidade e a sobrevida por câncer de próstata em Cuiabá e Várzea Grande, no período de 2000 a 2016. Métodos: Foram utilizados os dados do Registro de Câncer de Base Populacional e do Sistema de Informação sobre Mortalidade. Para a análise de tendência da incidência e mortalidade foi utilizada a regressão por Joinpoint segundo faixa etária. Para estimar a probabilidade de sobrevivência foi utilizado o método de Kaplan-Meier e para avaliar a associação com a faixa etária foi estimado hazard ratio. Resultados: De 2000 a 2016, foram registrados 3.671 casos novos e 892 óbitos por câncer de próstata. A média das taxas no período (100.000 habitantes) foi de 87,96 para incidência e 20,22 para mortalidade. Verificou-se tendência decrescente da taxa de incidência para todas as idades de 2006 a 2016 (APC=-3,2%) e para homens com 80 anos ou mais de 2000 a 2016 (APC=-3,0%), e tendência crescente da taxa de mortalidade nos homens de 60-69 anos de 2000 a 2009 (APC=3,2%). A probabilidade de sobrevida específica em cinco anos foi de 79,6% (IC95%: 77,2; 81,9), e diminuiu com o aumento da faixa etária (HR=2,43; IC95%: 1,5; 3,9 para aqueles de 70 a 79 anos e HR= 7,20; IC95%: 4,5;11,5 de 80 anos ou mais). Conclusão: A taxa de incidência de câncer de próstata apresentou tendência de decréscimo a partir de 2006 para todas as idades, a taxa de mortalidade foi estável no período, e pior prognóstico foi observado em homens com 70 anos ou mais.